Flavio H. Fenton on Google Scholar

2025

  • IL-1β enhances susceptibility to atrial fibrillation in mice by acting through resident macrophages and promoting caspase-1 expression.
    Moreno-Loaiza O, Soares VC, de Assumpção Souza M, Vera-Nuñez N, et al. Nature Cardiovascular Research.

2024

  • Disturbed repolarisation-relaxation coupling during acute ischaemia permits systolic mechano-arrhythmogenesis.
    Cameron BA, Baumeister PA, Lawen T, Rafferty SA, Taeb B, Stoyek MR, et al. bioRxiv.

  • Fast interactive simulations of cardiac electrical activity in anatomically accurate heart structures by compressing sparse uniform Cartesian grids.
    Kaboudian A, Gray RA, Uzelac I, Cherry EM, Fenton FH. Computer Methods and Programs in Biomedicine.

  • Mechanism of Arrhythmogenesis Driven by Early After Depolarizations in Cardiac Tissue.
    Stein J, Greene DA, Fenton F, Shiferaw Y. bioRxiv.

  • Experimental studies of spiral wave teleportation in a light-sensitive Belousov–Zhabotinsky system.
    Tyler SA, Mersing D, Fenton FH, Tinsley MR, Showalter K. Chaos: An Interdisciplinary Journal of Nonlinear Science.

  • A cross-species thermoelectric and spatiotemporal analysis of alternans in live explanted hearts using dual voltage-calcium fluorescence optical mapping.
    Crispino A, Loppini A, Uzelac I, Iravanian S, Bhatia NK, Burke M, et al. Physiological Measurement.

  • Divergent patterns: Contrasting voltage and calcium alternans between fish and human hearts.
    Chionuma H, Rheaume E, Uzelac I, Iravanian S, Bhatia NK, Burke M, et al. Heart Rhythm.

  • Pigmentation Pattern Recreation in Reaction-Diffusion Systems using Realistic Bounds.
    Cloonan A, Fenton F. APS March Meeting Abstracts.

  • Reproducing Experimentally Observed Alternans in Cardiac Tissue Using Fractional Diffusion.
    Jin L, Cherry EM, Fenton F, Uzelac I, Gizzi A. APS March Meeting Abstracts.

  • Chaos of Cardiac Tissue under Periodic Stimuli and Fibrillation: Experiments and Control.
    Toye M, Herndon C, Halprin M, Greiner E, Martsberger C, Fenton F. APS March Meeting Abstracts.

  • Complex repolarization dynamics in ex vivo human ventricles are independent of the restitution properties.
    Iravanian S, Uzelac I, Shah AD, Toye MJ, Lloyd MS, Burke MA, et al. Europace.

2023

  • Employing Gaussian process priors for studying spatial variation in the parameters of a cardiac action potential model.
    Ramos AN, Krapu CL, Cherry EM, Fenton FH. arXiv preprint.

  • Spatiotemporal Correlation Analysis of Cardiac Activation Patterns in Langendorff-Perfused Human Hearts: Insights for Arrhythmia Prediction.
    Crispino A, Loppini A, Uzelac I, Filippi S, Fenton FH, Gizzi A. Computing in Cardiology (CinC).

  • A combinatorial algorithm to detect higher-order dynamics in cardiac signals.
    Iravanian S, Toye MJ, Uzelac I, Bhatia NK, Cherry EM, Fenton FH. Computing in Cardiology (CinC).

  • Reconstructing Cardiac Voltage Using Data Assimilation: Effects of Observation Distribution.
    Badr S, Fenton FH, Cherry EM. Computing in Cardiology (CinC).

  • GPU load balancing using sparse Cartesian grids: Making interactive WebGL simulations of complex ionic models even faster on 3D heart structures.
    Kaboudian A, Cherry EM, Fenton FH. Computing in Cardiology (CinC).

  • Automated Customization of Cardiac Electrophysiology Models to Facilitate Patient-Specific Modeling.
    Cairns DI, Comstock MR, Fenton FH, Cherry EM. Computing in Cardiology (CinC).

  • Reconstructing cardiac electrical excitations from optical mapping recordings.
    Marcotte CD, Hoffman MJ, Fenton FH, Cherry EM. Chaos: An Interdisciplinary Journal of Nonlinear Science.

  • Ephaptic Coupling as a Resolution to the Paradox of Action Potential Wave Speed and Discordant Alternans Spatial Scales in the Heart.
    Otani NF, Figueroa E, Garrison J, Hewson M, Muñoz L, Fenton FH, et al. Physical Review Letters.

  • Beyond Alternans: Detection of Higher-Order Periodicity in Ex-Vivo Human Ventricles Before Induction of Ventricular Fibrillation.
    Iravanian S, Uzelac I, Shah AD, Toye MJ, Lloyd MS, Burke MA, et al. bioRxiv.

  • Role of ephaptic coupling in discordant alternans domain sizes and action potential propagation in the heart
    Otani NF, Figueroa E, Garrison J, Hewson M, Muñoz L, Fenton FH, et al. Physical Review E 107 (5), 054407.

  • PO-01-211 LONG-TIME MACHINE-LEARNING PREDICTION OF COMPLEX SPATIOTEMPORAL DYNAMICS DURING FIBRILLATION IN LIVE EXPLANTED PIG AND HUMAN HEARTS
    Fenton FH, Shahi S, Uzelac I, Iravanian S, Bhatia NK, Burke M, Shah AD, et al. Heart Rhythm 20 (5), S162.

  • PO-02-174 CHARACTERIZATION OF PAPILLARY MUSCLE ABLATION WITH OPTICAL MAPPING AT DIFFERENT TRANSMURAL PENETRATION DEPTHS IN LIVE HUMAN HEART
    Uzelac I, Iravanian S, Bhatia NK, Burke M, Shah AD, Gupta D, et al. Heart Rhythm 20 (S).

  • Optical mapping of contracting hearts
    Kappadan V, Sohi A, Parlitz U, Luther S, Uzelac I, Fenton FH, Peters NS, et al. The Journal of Physiology 601 (8), 1353-1370.

  • Experimental Quantification of Chaos in Cardiac Tissue; Examples of Period 3 and Other Complex Dynamics
    Toye M, Herndon C, Halprin M, Greiner E, Fenton FH. APS March Meeting Abstracts 2023, M10. 003.

  • Experiments and simulations of Turing patterns in vegetation
    Fenton FH, Daquino B, Toye M. APS March Meeting Abstracts 2023, Y14. 011.

  • Bayesian inference for fitting cardiac models to experiments: estimating parameter distributions using Hamiltonian Monte Carlo and approximate Bayesian computation
    Nieto Ramos A, Fenton FH, Cherry EM. Medical & Biological Engineering & Computing 61 (1), 75-95.

  • Cell Unexcitability and Electrotonic Coupling Phenomenon Analysis of Ablation-Created Lesions: A Study Case with Ablated Explanted Human Heart
    Paredes GS, Salinet J, Crowley C, Fenton FH, Bhatia N. Computing in Cardiology Conference (CinC) 49.

2022

  • Fiber organization has little effect on electrical activation patterns during focal arrhythmias in the left atrium
    He J, Pertsov AM, Cherry EM, Fenton FH, Roney CH, Niederer SA, Zang Z, et al. IEEE Transactions on Biomedical Engineering 70 (5), 1611-1621.

  • Spiral wave breakup: Optical mapping in an explanted human heart shows the transition from ventricular tachycardia to ventricular fibrillation and self-termination
    Uzelac I, Iravanian S, Bhatia NK, Fenton FH. Heart Rhythm 19 (11).

  • Direct observation of a stable spiral wave reentry in ventricles of a whole human heart using optical mapping for voltage and calcium
    Uzelac I, Iravanian S, Bhatia NK, Fenton FH. Heart Rhythm 19 (11), 1912-1913.

  • Methodological analysis of dual voltage-calcium whole-heart optical signals during restitution pacing under different thermal states
    Crispino A, Loppini A, Uzelac I, Fenton FH, Gizzi A, Filippi S. 2022 12th Conference of the European Study Group on Cardiovascular…

  • Optical Ultrastructure of Cardiac Tissue Helps to Reproduce Discordant Alternans by In Silico Data Assimilation
    Hörning M, Loppini A, Erhardt J, Fenton FH, Filippi S, Gizzi A. 2022 12th Conference of the European Study Group on Cardiovascular…

  • Cell Unexcitability and Electrotonic Coupling Phenomenon Analysis of Ablation-Created Lesions: A Study Case with Ablated Explanted Human Heart
    Siles J, Salinet J, Crowley C, Fenton FH, Bhatia N, Iravanian S, Uzelac I. 2022 Computing in Cardiology (CinC) 498, 1-4.

  • Circle method for robust estimation of local conduction velocity high-density maps from optical mapping data: Characterization of radiofrequency ablation sites
    Siles-Paredes JG, Crowley CJ, Fenton FH, Bhatia NK, Iravanian S, et al. Frontiers in Physiology 13, 794761.

  • Prediction of chaotic time series using recurrent neural networks and reservoir computing techniques: A comparative study
    Shahi S, Fenton FH, Cherry EM. Machine Learning with Applications 8, 100300.

  • Terminating spiral waves with a single designed stimulus: Teleportation as the mechanism for defibrillation
    DeTal N, Kaboudian A, Fenton FH. Proceedings of the National Academy of Sciences 119 (24), e2117568119.

  • A machine-learning approach for long-term prediction of experimental cardiac action potential time series using an autoencoder and echo state networks
    Shahi S, Fenton FH, Cherry EM. Chaos: An Interdisciplinary Journal of Nonlinear Science 32 (6).

  • PO-691-07 SIMULTANEOUS OPTICAL MAPPING MEASUREMENTS OF VOLTAGE AND CALCIUM IN WHOLE EXPLANTED HUMAN HEARTS
    Uzelac I, Kim TY, Iravanian S, Cherry EM, Bhatia NK, Chionuma H, Burke M, et al. Heart Rhythm 19 (5), S401.

  • PO-691-05 First experimental observation of alternans-induced phase-2 reentry in Brugada syndrome by optical mapping on an explanted human heart, with numerical simulation…
    Fenton FH, Kim TY, Cherry EM, Uzelac I, Iravanian S, Cho HC, et al. Heart Rhythm 19 (5), S400.

  • PO-705-01 ACTION POTENTIAL RESTITUTION CURVES OBTAINED FROM FULL EXPLANTED HUMAN HEARTS
    Bhatia NK, Merchant FM, Lloyd MS, El-Chami MF, Iravanian S, Kim TY, et al. Heart Rhythm 19 (5), S453-S454.

  • PO-616-01 ROTOR LOCALIZATION AND PHASE MAPPING OF CARDIAC EXCITATION WAVES USING DEEP NEURAL NETWORKS
    Lebert J, Ravi N, Fenton FH, Christoph J. Heart Rhythm 19 (5), S110-S111.

  • BS-516-02 OPTICAL MAPPING OF EXPLANTED HUMAN HEARTS ENABLES REFINED IONIC MODELS OF ACTION POTENTIAL AND CONDUCTION VELOCITY RESTITUTION CURVES FOR ARRHYTHMIA SIMULATION
    Kim TY, Cherry EM, Iravanian S, Uzelac I, Chionuma H, Bhatia NK, et al. Heart Rhythm 19 (5), S83-S84.

  • PO-616-06 THE SPATIOTEMPORAL ORGANIZATION OF VENTRICULAR FIBRILLATION (VF) IN EXPLANTED HUMAN HEARTS
    Iravanian S, Uzelac I, Bhatia NK, Kim TY, Cherry EM, Chionuma H, et al. Heart Rhythm 19 (5), S112-S113.

  • Optical Ultrastructure of Large Mammalian Hearts Recovers Discordant Alternans by In Silico Data Assimilation
    Loppini A, Erhardt J, Fenton FH, Filippi S, Hörning M, Gizzi A. Frontiers in Network Physiology 2, 866101.

  • Methodology for cross-talk elimination in simultaneous voltage and calcium optical mapping measurements with semasbestic wavelengths
    Uzelac I, Crowley CJ, Iravanian S, Kim TY, Cho HC, Fenton FH. Frontiers in Physiology 13, 812968.

  • Voltage-mediated mechanism for calcium wave synchronization and arrhythmogenesis in atrial tissue
    Greene DA, Kaboudian A, Wasserstrom JA, Fenton FH, Shiferaw Y. Biophysical Journal 121 (3), 383-395.

  • Rotor localization and phase mapping of cardiac excitation waves using deep neural networks
    Lebert J, Ravi N, Fenton FH, Christoph J. Frontiers in Physiology 12, 782176.

2021

  • Control and anticontrol of chaos in fractional-order models of Diabetes, HIV, Dengue, Migraine, Parkinson’s and Ebola virus diseases
    Borah M, Das D, Gayan A, Fenton FH, Cherry EM. Chaos, Solitons & Fractals 153, 111419.

  • A new simple model for cardiac alternans
    Velasco Perez H, Fenton FH. Bulletin of the American Physical Society 66.

  • Long-time prediction of arrhythmic cardiac action potentials using recurrent neural networks and reservoir computing
    Shahi S, Marcotte CD, Herndon CJ, Fenton FH, Shiferaw Y, Cherry EM. Frontiers in Physiology 12, 734178.

  • Optimizing low-energy anti-fibrillation pacing: Lessons from a cellular automaton model
    DeTal N, Fenton FH. arXiv preprint arXiv:2109.10861.

  • Interactive 3D human heart simulations on segmented human MRI hearts
    Berman JP, Kaboudian A, Uzelac I, Iravanian S, Iles T, Iaizzo PA, Lim H, et al. 2021 Computing in Cardiology (CinC) 48, 1-4.

  • A network-based cardiac electrophysiology simulator with realistic signal generation and response to pacing maneuvers
    Iravanian S, Uzelac I, Kaboudian A, Langberg J, Fenton FH. 2021 Computing in Cardiology (CinC) 48, 1-4.

  • Interactive Simulation of the ECG: Effects of Cell Types, Distributions, Shapes and Duration
    Ortiz JR, Kaboudian A, Uzelac I, Iravanian S, Cherry EM, Fenton FH. 2021 Computing in Cardiology (CinC) 48, 1-4.

  • Unimapper: An online interactive analyzer/visualizer of optical mapping experimental data
    Iravanian S, Uzelac I, Cairns DI, Cherry EM, Kaboudian A, Fenton FH. 2021 Computing in Cardiology (CinC) 48, 1-4.

  • Not all Long-QTs Are The Same, Proarrhythmic Quantification with Action Potential Triangulation and Alternans
    Uzelac I, Iravanian S, Cherry EM, Fenton FH. 2021 Computing in Cardiology (CinC) 48, 1-4.

  • Real-time interactive simulations of complex ionic cardiac cell models in 2D and 3D heart structures with GPUs on personal computers
    Kaboudian A, Cherry EM, Fenton FH. 2021 Computing in Cardiology (CinC) 48, 1-4.

  • Quantifying distributions of parameters for cardiac action potential models using the Hamiltonian Monte Carlo method
    Ramos AN, Herndon CJ, Fenton FH, Cherry EM. 2021 Computing in Cardiology (CinC) 48, 1-4.

  • Quantifying arrhythmic long QT effects of hydroxychloroquine and azithromycin with whole-heart optical mapping and simulations
    Uzelac I, Kaboudian A, Iravanian S, Siles-Paredes JG, Gumbart JC, et al. Heart Rhythm O2 2 (4), 394-404.

  • Arrhythmogenic effects of genetic mutations affecting potassium channels in human atrial fibrillation: a simulation study
    Belletti R, Romero L, Martinez-Mateu L, Cherry EM, Fenton FH, Saiz J. Frontiers in Physiology 12, 681943.

  • Thermal effects on cardiac alternans onset and development: A spatiotemporal correlation analysis
    Loppini A, Barone A, Gizzi A, Cherubini C, Fenton FH, Filippi S. Physical Review E 103 (4), L040201.

  • Experiments and simulations to quantify the arrhythmic effects of Hydroxychloroquine (HCQ) and azithromycin (AZM) in the treatment of COVID19
    F Fenton
    APS March Meeting Abstracts 2021, P01. 002

  • Real-time control of a period doubling bifurcation in frog hearts
    M Halprin, C Herndon, F Fenton
    APS March Meeting Abstracts 2021, B36. 005

  • Chimeras as a way to model anatomical reentry in cardiac models
    A Welsh, F Fenton
    APS March Meeting Abstracts 2021, J12. 007

  • Defibrillate you later, Alligator: Q10 scaling and refractoriness keeps alligators from fibrillation
    C Herndon, HC Astley, T Owerkowicz, FH Fenton
    Integrative Organismal Biology 3 (1), obaa047

  • Robust data assimilation with noise: Applications to cardiac dynamicsCD Marcotte, FH Fenton, MJ Hoffman, EM Cherry Chaos: An Interdisciplinary Journal of Nonlinear Science 31 (1), 013118

2020

  • Experimental validation of a variational data assimilation procedure for estimating space-dependent cardiac conductivitiesA Barone, A Gizzi, F Fenton, S Filippi, A Veneziani Computer Methods in Applied Mechanics and Engineering 358, 112615
  • Generation of Monophasic Action Potentials and Intermediate FormsS Iravanian, I Uzelac, C Herndon, JJ Langberg, FH Fenton Biophysical Journal 119 (2), 460-469
  • High-resolution optical measurement of cardiac restitution, contraction, and fibrillation dynamics in beating vs. blebbistatin-uncoupled isolated rabbit heartsV Kappadan, S Telele, I Uzelac, F Fenton, U Parlitz, S Luther, J Christoph Frontiers in Physiology 11, 464
  • Accelerating simulations of cardiac electrical dynamics through a multi‐GPU platform and an optimized data structureEC Vasconcellos, EWG Clua, FH Fenton, M Zamith Concurrency and Computation: Practice and Experience 32 (5), e5528
  • Excitable dynamics in neural and cardiac systemsR Barrio, S Coombes, M Desroches, F Fenton, S Luther, E Pueyo Communications in Nonlinear Science and Numerical Simulation 86, 105275
  • Key aspects for effective mathematical modelling of fractional-diffusion in cardiac electrophysiology: A quantitative studyN Cusimano, A Gizzi, FH Fenton, S Filippi, L Gerardo-Giorda Communications in Nonlinear Science and Numerical Simulation 84, 105152
  • Fatal arrhythmias: Another reason why doctors remain cautious about chloroquine/hydroxychloroquine for treating COVID-19I Uzelac, S Iravanian, H Ashikaga, NK Bhatia, C Herndon, A Kaboudian, JC Gumbart, EM Cherry, FH Fenton Heart rhythm 17 (9), 1445-1451
  • Creation and application of virtual patient cohorts of heart modelsSA Niederer, Y Aboelkassem, CD Cantwell, C Corrado, S Coveney, EM Cherry, T Delhaas, FH Fenton, AV Panfilov, P Pathmanathan, G Plank, M Riabiz, CH Roney, RW Dos Santos, L Wang Philosophical Transactions of the Royal Society A 378 (2173), 20190558
  • Data-Driven Uncertainty Quantification for Cardiac Electrophysiological Models: Impact of Physiological Variability on Action Potential and Spiral Wave DynamicsSP Pathmanathan, SK Galappaththige, JM Cordeiro, A Kaboudian, FH Fenton, Richard A Gray Frontiers in physiology 11, 1463
  • Robust data assimilation with noise: Applications to cardiac dynamics
    CD Marcotte, FH Fenton, MJ Hoffman, EM Cherry Chaos: An Interdisciplinary Journal of Nonlinear Science 31 (1), 013118

2019

  • Patterns and HumansN Manz, FH Fenton Spirals and Vortices, 217-224
  • Theoretical modeling and experimental detection of the extracellular phasic impedance modulation in rabbit heartsS Iravanian, C Herndon, JJ Langberg, FH Fenton Frontiers in physiology 10, 883
  • A Comprehensive Comparison of GPU Implementations of Cardiac Electrophysiology ModelsA Kaboudian, HA Velasco-Perez, S Iravanian, Y Shiferaw, EM Cherry, FH Fenton From Reactive Systems to Cyber-Physical Systems, 9-34
  • Real-time interactive simulations of large-scale systems on personal computers and cell phones: Toward patient-specific heart modeling and other applicationsA Kaboudian, EM Cherry, FH Fentonn Science advances 5 (3), eaav6019
  • Large-scale interactive numerical experiments of chaos, solitons and fractals in real time via GPU in a web browserA Kaboudian, EM Cherry, FH Fenton Chaos, Solitons & Fractals 121, 6-29
  • Probabilistic reachability for multi-parameter bifurcation analysis of cardiac alternansMA Islam, R Cleaveland, FH Fenton, R Grosu, PL Jones, SA Smolka Theoretical Computer Science 765, 158-169
  • Simulating normal and arrhythmic dynamics: From sub-cellular to tissue and organ levelH Dierckx, FH Fenton, S Filippi, A Pumir, S Sridhar Frontiers in Physics 7, 89:
  • Spatiotemporal correlation uncovers characteristic lengths in cardiac tissueA Loppini, A Gizzi, C Cherubini, EM Cherry, FH Fenton, S Filippi Physical Review E 100 (2), 020201
  • Isosbestic Point in Optical Mapping; Theoretical and Experimental Determination With Di-4-ANBDQPQ Transmembrane Voltage Sensitive DyeI Uzelac, CJ Crowley, FH Fenton 2019 Computing in Cardiology (CinC), 1-4
  • Baseline Wandering Removal in Optical Mapping Measurements With PID Control in Phase Space
    S Eisner, FH Fenton, I Uzelac 2019 Computing in Cardiology (CinC), 1-4
  • Parallel Acceleration on Removal of Optical Mapping Baseline WanderingI Uzelac, S Iravanian, FH Fenton 2019 Computing in Cardiology (CinC), 1-4
  • Visualizing dynamical systems with fire frontsN Manz, F Fenton Bulletin of the American Physical Society 64
  • Engineered Cardiac Pacemaker Nodes Created by TBX18 Gene Transfer Overcome Source–Sink MismatchSI Grijalva, J Gu, J Li, N Fernandez, J Fan, JH Sung, SY Lee, C Herndon, EM Buckley, SJ Park, FH Fenton, HC Cho Advanced Science 6 (22), 1901099
  • Simulating waves, chaos and synchronization with a microcontrollerAJ Welsh, C Delgado, C Lee-Trimble, A Kaboudian, FH Fenton Chaos: An Interdisciplinary Journal of Nonlinear Science 29 (12), 123104

2018

  • Electromechanical vortex filaments during cardiac fibrillation
    Christoph J, Chebbok M, Richter C, Schroder-Schetelig J, Bittihn P, Stein S, Uzelac I, Fenton FH, Hasenfuss G, Gilmour RF, Luther S. Nature, 555(7698)
  • Probabilistic reachability for multi-parameter bifurcation analysis of cardiac alternansIslam MA, Cleaveland R, Fenton FH, Grosu R, Jones PL, Smolka SA. Theoretical Computer Science, in press
  • Spatiotemporal correlation uncovers fractional scaling in cardiac tissueA Loppini, A Gizzi, C Cherubini, EM Cherry, FH Fenton, S Filippi arXiv preprint arXiv: 1806.04507
  • Discordant alternans as a mechanism for initiation of ventricular fibrillation In vitroLaura M Muñoz, Anna RM Gelzer, Flavio H Fenton, Wei Qian, WeiYe Lin, Robert F Gilmour Jr, Niels F Otani Journal of the American Heart Association 7 (17), e007898
  • Competing mechanisms of stress-assisted diffusivity and stretch-activated currents in cardiac electromechanicsA Loppini, A Gizzi, R Ruiz-Baier, C Cherubini, FH Fenton, S Filippi JFrontiers in physiology 9, 1714

2017

  • Introduction to Focus Issue: Complex Cardiac DynamicsCherry EM, Fenton FH, Krogh-Madsen T, Luther S, Parlitz U. Chaos, 27(9)
  • Numerical sensitivity analysis of a variational data assimilation procedure for cardiac conductivitiesBarone A, Fenton FH, Veneziani A. Chaos, 27(9)
  • Efficient parameterization of cardiac action potential models using a genetic algorithm
    Cairns D, Fenton FH, Cherry EM. Chaos, 27(9)
  • Synchronization as a mechanism for low-energy anti-fibrillation pacingJi Y, Uzelac I, Otani N, Luther S, Gilmour RF, Cherry EM, Fenton FH. Heart Rhythm, 14(8)
  • Multi-band decomposition analysis: application to cardiac alternans as a function of temperatureGizzi A, Loppini A, Cherry EM, Cherubini C, Fenton FH, Filippi S. Physiological Measurement, 38(5)
  • Mechanism for amplitude alternans in electrocardiograms and the initiation of spatiotemporal chaosChen D, Gray RA, Uzelac I, Herndon C, Fenton FH. Physical Review Letters, 118(16)
  • Level-set Method for Robust Analysis of Optical Mapping Recordings of FibrillationGurevich D, Herndon C, Uzelac I, Fenton FH, Grigoriev R. Computing in Cardiology, 44
  • Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac Action Potentials and Ca TransientsUzelac I, Ji Y, Hornung D, Schroder-Scheteling J, Luther S, Gray R, Cherry EM, Fenton FH. Frontiers in Physiology, 8(819)
  • Dynamics of a human spiral wave
    Welsh A, Greco E, Fenton FH. Physics Today, 70(2)

2016

  • Computational ECG reconstruction and validation from high-resolution optical mappingHerndon C, Uzelac I, Farmer JT, Fenton FH. Computing in Cardiology
  • Electrocardiogram reconstruction from high resolution voltage optical mappingUzelac I, Herndon C, Farmer JT, Fenton FH. IEEE Engineering in Medicine and Biology Society
  • Book review: Patterns in Excitable Media: Genesis, Dynamics, and ControlFenton FH Physics today, 69 (2), 48
  • Reconstructing three-dimensional reentrant cardiac electrical wave dynamics using data assimilationHoffman NJ, LaVigne NS, Scorse ST, Fenton FH, Cherry EM Chaos, 26 (1), 013107
  • Sharp Boundary Electrocardiac SimulationsXue S, Lim H, Glimm J, Fenton FH, Cherry EM, SIAM Journal on Scientific Computing, 38 (1), B100-B117
  • Numerical solutions of reaction-diffusion equations: Application to neural and cardiac modelsJi YC, Fenton FH, American Journal of Physics, 84 (626)

2015

  • Basis for the Induction of Tissue-Level Phase-2 Reentry as a Repolarization Disorder in the Brugada SyndromeBueno-Orovio A, Cherry EM, Evans SJ, Fenton FH BioMed Research International, 197586, 12 pages
  • Implementation of Contraction to Electrophysiological Ventricular Myocyte Models, and Their Quantitative Characterization via Post-Extrasystolic PotentiationJi YC, Gray RA, Fenton FH PloS One, 10 (8), e0135699
  • Model-order reduction of ion channel dynamics using approximate bisimulationIslam MA, Murthy A, Bartocci E, Cherry EM, Fenton FH, Glimm J, Smolka SA, Grosu R. Theoretical Computer Science, 599, 34-46
  • Robust Framework for Quantitative Analysis of Optical Mapping Signal without FilteringUzelac I, Fenton FH. Computers in Cardiology, 461-464

2014

  • Mechanistic insights into hypothermic ventricular fibrillation: the role of temperature and tissue sizeFilippi S, Gizzi A, Cherubini C, Luther S, Fenton FH Europace, 16 (3), 424-434,
  • Spatio-temporal correlation of paced cardiac tissueFilippi S, Cherubini C, Gizzi A, Loppini A, Fenton FH . Cardiovascular Oscillations (ESGCO), IEEE, 223-224
  • Continuous-time control of alternans in long Purkinje fibersGarzon A, Grigoriev RO, Fenton FH , Chaos, 24 (3), 033124
  • Modelling the take-off voltage of the action potential during fast pacingChen DD, Gray RA, Fenton FH , Computing in Cardiology Conference (CinC), 685-688
  • Compositional, approximate, and quantitative reasoning for medical cyber-physical systems with application to patient-specific cardiac dynamics and devicesGrosu R, Cherry EM, Clarke EM, Cleaveland R, Dixit S, Fenton FH, Gao S, Glimm J, Gray RA, Mangharam R, Ray A, Smolka SA Leveraging Applications of Formal Methods, Verification and Validation. Specialized Techniques and Applications, 356-364

2013

  • Validation of a computational model of cardiac defibrillationBragard J, Elorza J, Cherry EM, Fenton FH Computing in Cardiology (CinC), 851-854,
  • High-power current source with real-time arbitrary waveforms for in vivo and in vitro studies of defibrillationUzelac I, Holcomb M, Reiserer RS, Fenton FH, Wikswo JP Computing in Cardiology (CinC), 667-670
  • Subepicardial action potential characteristics are a function of depth and activation sequence in isolated rabbit heartsKelly A, Ghouri IA, Kemi OJ, Bishop MJ, Bernus O, Fenton FH, Myles RC, Circulation: Arrhythmia and Electrophysiology, 6 (4), 809-817
  • Role of temperature on nonlinear cardiac dynamicsFH Fenton, A Gizzi, C Cherubini, N Pomella, S Filippi , Physical Review E, 87 (4), 042717
  • Curvature analysis of cardiac excitation wavefrontsMurthy A, Bartocci E, Fenton FH, Glimm J, Gray R, Cherry RM, Smolka S, Computational Biology and Bioinformatics, IEEE/ACM Transactions
  • Study of Cardiac Defibrillation Through Numerical SimulationsBragard J, Marin S, Cherry EM, Fenton FH Without Bounds: A Scientific Canvas of Nonlinearity and Complex Dynamics
  • Effects of pacing site and stimulation history on alternans dynamics and the development of complex spatiotemporal patterns in cardiac tissue
    Gizzi A, Cherry EM, GilmourJr RF, Luther S, Filippi S, Fenton FH Frontiers in physiology, 4

2012

  • Contribution of the Purkinje network to wave propagation in the canine ventricle: insights from a combined electrophysiological-anatomical model.
    Cherry EM, Fenton FH. Nonlinear Dynamics, 68 (3), 365-379
  • Mechanisms of ventricular arrhythmias: a dynamical systems-based perspective
    Cherry EM, Fenton FH, Gilmour RF American Journal of Physiology-Heart and Circulatory Physiology
  • Low-energy anti-fibrillation pacing (LEAP): A gentle, non traumatic defibrillation optionEuropean Heart Journal, 33, 381-3812012
  • Approximate bisimulations for sodium channel dynamicsMurthy A, Islam M, Bartocci E, Cherry EM, Fenton RH, Glimm J, Computational Methods in Systems Biology, 267-287

2011

  • Low-energy control of electrical turbulence in the heartLuther S*, Fenton FH*, Kornreich BG, Squires A, Bittihn P, Hornung D, Zabel M, Flanders J, Gladuli A, Campoy L, Cherry EM, Luther G, Hasenfuss G, Krinsky VI, Pumir A, Gilmour RF Jr, Bodenschatz E. Nature, Jul 13; 475(7355):235-9(*) Equal first authors.
  • Effects of boundaries and geometry on the spatial distribution of action potential duration in cardiac tissueCherry EM, Fenton FH. Journal of Theoretical Biology, Vol 285, 164-176
  • Toward Real-time Simulation of Cardiac DynamicsBartocci E, Cherry EM, Glimm J, Grosu R, Smolka SA, Fenton FH. , CMSB 2011 9th International Conference on Computational Methods in Systems Biology, Sept. 21-23 pages 103-110
  • Curvature Analysis of Cardiac Excitation WavefrontsMurthy A, Bartocci E, Fenton FH, Glimm J, Gray RA, Smolka SA, and Grosu R. , CMSB 2011 9th International Conference on Computational Methods in Systems Biology, Sept. 21-23 pages 151-160
  • From Cardiac Cells to Genetic Regulatory NetworksGrosu R, Batt G, Fenton FH, Glimm J, Le Guernic C, Smolka SA, Bartocci E. International Conference on Computer Aided Verification, 6806, pp. 396-411
  • Verification of cardiac tissue electrophysiology simulations using an N-version benchmarkNiederer SA, Kerfoot E, Benson A, Bernabeu MO, Bernus O, Bradley C, Cherry EM, Clayton R, Fenton FH, Garny A, Heidenreich E, Land S, Maleckar M, Pathmanathan P, Plank G, Rodriguez JF, Roy I, Sachse FB, Seemann G, Skavhaug O, Smith NP. Transactions of the Royal Society A
  • Models of cardiac tissue electrophysiology: Progress, challenges and open questionsClayton RH, Bernus O; Cherry EM; Dierckx H; Fenton FH, Mirabella L, Panfilov S V, Sachse FB, Seeman G; Zhang H. Prog Biophys Mol Biol, 104; 22-48
  • Cardiac cell modeling: Observations from the heart of the cardiac physiome projectFink M, Niederer SA, Cherry EM, Fenton FH, Koivumäki JT, Seemann G, Thul R, Zhang H, Sachse FB, Beard D, Crampin EJ, Smith NP. , Prog Biophys Mol Biol, 104; 2-21
  • From cardiac cells to genetic regulatory networksGrosu R, Batt G, Fenton FH, Glimm J, Guernic C Le, Smolka SA, Bartocci E. Computer Aided Verification, 396-411
  • A Change of Perspective Yields Formal AnalysisGrosu R, Fenton FH, Smolka S, Bartocci E. Software Engineering Workshop (SEW), 34th IEEE, 69-76
  • Model-based control of cardiac alternans in Purkinje fibersGarzon A, Grigoriev RO, FH Fenton FH Physical Review E 84 (4), 041927
  • Teaching cardiac electrophysiology modeling to undergraduate students: laboratory exercises and GPU programming for the study of arrhythmias and spiral wave dynamicsBartocci E, Singh R, von Stein FB, Fenton FH. Advances in physiology education, 35 (4), 427-437
  • The Value of SimulationFenton FH. Physics World, 23:46-47

2010

  • Realistic cardiac electrophysiology modeling: are we just a heartbeat away?
    Cherry EM and Fenton FH. J. Physiol. 588, 2689

2009

  • Termination of atrial fibrillation using pulsed low-energy far field stimulationFenton FH, Luther S, Otani NF, Cherry EM, Pumir A, Bodenschatz E, Krinsky V, Gilmour RF Jr. Circulation, 120, 467-476
  • Use of Ultrasound Imaging to Map Propagating Action Potential Waves in the HeartOtani NF, Singh R, Fenton FH, Butcher J, DW Infanger DW, Neumann A, Luther S, Gilmour Jr RF. Computers in Cardiology
  • Model-based control of cardiac alternans on a ringGarzon A, Roman OG, Fenton FH. Physical Review E, 80:021932

2008

  • Visualization of spiral and scroll waves in simulated and experimental cardiac tissueCherry EM, Fenton FH. New J. Phys, 10 125016(Selected as New Journal of Physics Best of 2008 by the editors)
  • Models of cardiac cellFenton FH., Cherry EM. Scholarpedia, 3(8):1868
  • Termination of equine atrial fibrillation by quinidine: An optical mapping studyFenton FH, Cherry EM, Kornreich BG. Journal of Veterinary Cardiology, 10 87-102 (Article featured in the Journal Cover)
  • Predator-prey approach to analyzing complex dynamics in cardiac tissueOtani NF, Mo A, Mannava S, Fenton FH, Cherry EM, Luther S, Gilmour RF, Jr. Physical Review E, 78, 021913
  • Cardiac arrhythmiaFenton FH, Cherry EM, Glass Leon. Scholarpedia; 3(7):1665
  • Minimal Model for Human Ventricular Action Potential in TissueBueno-Orovio A., Cherry EM, Fenton FH. Journal of Theoretical Biology; 253: 544-560

2007

  • Pulmonary Vein Reentry-Properties and Size Matter: Insights from a Computational AnalysisCherry EM., Ehrlich JR, Nattel S, Fenton FH. Heart Rhythm 2007; 12: 1553-1562 (Article featured in the Journal Cover)
  • A tale of two dogs: analyzing two models of canine ventricular electrophysiologyCherry EM, Fenton FH. American Journal of Physiology 2007; 292: H43-H55

2006

  • Spectral Methods for Partial Differential Equations in Irregular Domains: The Spectral Smoothed Boundary MethodBueno-Orovio A., Perez-Garcia VM., and Fenton FH. SIAM Journal on Scientific Computing 2006; Vol. 28, N.3; 886-900
  • Reentrant arrhythmias in human ventricular modelsFenton FH, Orovio AB, Evans SJ, Cherry EM Heart Rhythm 2006 3 (5) S186
  • Tissue dynamics of two models of canine ventricular cell electrophysiology: Restitution, memory and reentry propertiesCherry EM, Gilmour RF, Fenton FH Heart Rhythm 2006 3 (5) S227
  • Web-based programs for learning cardiac electrophysiology: Interaactive simulations of heart cells and tissueFenton FH, Cherry EM, Hastings, HM, Evans SJ Heart Rhythm 2006 3 (5) S136

2005

  • Modeling Wave Propagation in Realistic Heart Geometries Using the Phase-Field MethodFenton FH., Cherry EM., Karma A., Rappel WJ. Chaos 2005; 15: 013502
  • Head-tail interactions in numerical simulations of reentry in a ring of cardiac tissueChen X, Fenton FH, Gray RA Heart Rhythm 2005 ; 2 (9), 1038-1046
  • Fibrillation without alternans in porcine ventricles
    Fenton FH, Cherry EM, Gray RA, Hastings HM, Evans SJ. Heart Rhythm 2005 2 (5) S301-S302

2004

  • Suppression of Alternans and Conduction Blocks Despite Steep APD Restitution: Electrotonic, Memory and Conduction Velocity Restitution EffectsCherry EM, Fenton FH. American Journal of Physiology 2004; 286: H2332-2341
  • A simulation study of atrial fibrillation initiation: Differences in resting membrane potential can produce spontaneous activations at the pulmonary vein-left atrial junction
    Fenton FH, Cherry EM, Ehrlich JR, Nattel S, Evans SJ. Heart Rhythm 2004 1 S187-S188

2003

  • Effects of wall heterogeneity in an anatomically realistic model of canine ventricles: A simulation studyCherry EM, Rappel WJ, Evans SJ, Fenton F PACE 2003 26, 1109

2002

  • Multiple mechanisms of spiral wave breakup in a model of cardiac electrical activityFenton FH, Cherry EM, Hastings HM, Evans SJ. Chaos 2002; 12: 852-892
  • Real-time Computer Simulations of Excitable Media: Java as a Scientific Language and as a Wrapper for C and Fortran ProgramsFenton FH, Cherry EM, Hastings HM, Evans SJ. BioSystems 2002; 64: 73-96

2001

  • Mechanisms for Discordant AlternansWatanabe M, Fenton F, Evans S, Hastings H, Karma A. Journal of Cardiovascular Electrophysiology 2001; 12: 196-206

2000

  • Alternans and the Onset to Ventricular FibrillationHastings H, Fenton F, Evans SJE, Hotomaroglu O, Geetha J, Gittelson K, Nilson J, Garfinkel A. Physical Review E 2000; 62: 4043-4048
  • Transition from ventricular tachycardia to ventricular fibrillation as a function of tissue characteristics in a computer modelFenton F, Karma A, Hastings H, Evans SJE. Europace 1 2000
  • Numerical Simulations of Cardiac Dynamics. What can we learn from simple and complex models?Fenton F. H. Computers in Cardiology 2000; 251-254

1999

  • Memory in an excitable medium; A mechanism for spiral wave breakup in the low-excitability limitFenton F, Evans S, Hastings H. Physical Review Letters 1999; 83: 3964-3967
  • Spatiotemporal Control of Wave Instabilities in Cardiac TissueRappel WJ, Fenton F, Karma A. Physical Review Letters 1999; 83: 456-459

1998

  • Instability of Electrical Vortex Filament and Wave Turbulence in Thick Cardiac MuscleFenton F, Karma A. Physical Review Letters 1998; 81: 481-484
  • Vortex Dynamics in 3D Continuous Myocardium With Fiber Rotation: Filament Instability and FibrillationFenton F, Karma A. Chaos 1998; 8: 20-47. (Errata for table: Chaos 1998; 8: 879.)

1997

  • A new three-variable mathematical model of action potential propagation in cardiac tissueFenton F, Karma A. APS March Meeting Abstract Vol 1. pg. 2012